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  • Medicare rules may reduce prescription steering January 14, 2025
    Weill Cornell Medicine researchers found that pharmacy benefit managers in integrated health care conglomerates, including CVS, UnitedHealth Group, Cigna and Humana, have a lower market share in Medicare than national estimates suggest.
  • FDA grants ALG-801 orphan drug designation for treatment of pulmonary arterial hypertension January 14, 2025
    The FDA has granted an orphan drug designation to ALG-801 for treating pulmonary arterial hypertension, a rare and life-threatening condition. ALG-801, a novel next-generation ActRII/IIB hybrid ligand trap, has demonstrated superior efficacy and improved safety in preclinical and clinical phase 1 studies.
  • Glucarpidase boosts recovery from methotrexate-induced acute kidney injury January 14, 2025
    Researchers at Brigham and Women's Hospital have found that glucarpidase significantly improves kidney recovery in patients with methotrexate-induced nephrotoxicity. The study, which analyzed data from over 700 patients across 28 U.S. cancer centers, is the first comprehensive study to include a control group and adjust for confounders.

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